CHEJ highlights many toxic chemicals and the communities fighting to keep their citizens safe from harm.
1,2-dichloroethane (1,2-D) – also called ethylene dichloride – is a clear, oily liquid with a sweet smell that is man-made and not found in nature. It is used in the production of plastic and vinyl products like polyvinyl chloride (PVC) pipes, upholstery, automobile parts, and housewares.
1,3-butadiene is a gas made from petroleum and is used to manufacture materials like synthetic rubber and plastics. Because it is a gas, 1,3-butadiene can easily leak out of production, storage, or disposal containers and enter the air. People who work in or live near facilities using 1,3-butadiene are most
1,4-dichlorobenzene (1,4-DCB) – also known as p-dichlorobenzene (p-DCB) – is a colorless solid chemical that readily evaporates into the air. 1,4-DCB does not occur in nature, and it is often produced for use in deodorants or disinfectants because it has a strong odor that humans can smell at very low
1,4-dioxane is a clear liquid used in chemical manufacturing for industrial, consumer, and military purposes. During manufacturing or improper waste disposal 1,4-dioxane can be released into the environment. While it breaks down in air and doesn’t stick to soil, 1,4-dioxane is stable in water and can remain there for a
2-Butanone is an industrial chemical that is also known as methyl ethyl ketone (MEK). It manifests itself as a colorless liquid under standard conditions, tends to evaporate into the air (volatize) quickly, and is quite flammable. 2-Butanone is manufactured in large amounts for use in paints, glues, and other finishes
Arsenic is a naturally-occurring element found in the Earth’s crust. It has some industrial uses through which people can become exposed to it. In some places, like northern New England, arsenic is present in bedrock, and drinking water wells drilled in these areas can expose people to arsenic in their
In October 2021, residents of Carson, California began smelling odors and experiencing dizziness, headaches, and nausea. The odor was identified as being hydrogen sulfide, and its concentration in the air remained above California’s air quality standards for three months. (CHEJ has previously written about hydrogen sulfide and its health effects
Approximately 1 year ago a Norfolk Southern train carrying more than 150 cars, many of which containing toxic chemicals derailed in East Palestine, OH. Thirty-eight of the train cars derailed and a decision was made by Norfolk Southern to burn the contents of 5 tanker cars containing vinyl chloride and
Acrolein is a toxic chemical that presents itself as a clear to yellowish liquid that evaporates quickly and is highly flammable. As it vaporizes, it has an unpleasant smell and tends to accumulate in low areas since it is heavier than air.
Inhaling airborne acrylonitrile can cause respiratory, skin, and
Acrylamide is a clear, odorless chemical. It has many industrial uses, including treating waste water
discharge from water treatment plants. It is also used in the production of industrial products like dyes,
paper pulp, grout, plastics, and construction materials. Many consumer products are also produced
using acrylamide, such as contact
Acrylonitrile is a clear liquid that smells like onions or garlic. It is man-made as it does not naturally occur on Earth. It is used to create other materials, most commonly acrylic fibers in clothing and carpeting. Acrylonitrile can enter the environment from industrial sites that produce it and waste
Aniline is a yellow liquid that smells like rotten fish and easily catches fire. It was first discovered in the 1800s and used as a synthetic dye for textiles. Aniline is now also used in the production of products like herbicides, agricultural chemicals, antioxidants, varnishes, rubber, polyurethane, and explosives. Aniline
Arsenic is a naturally-occurring element found throughout the Earth’s crust. It is usually found combined with other elements creating a powder that is odorless and tasteless and can exist either in an organic or inorganic form. Inorganic arsenic compounds are highly toxic and for years were used to preserve wood.
It’s the Christmas season, and because real pine trees can be cumbersome and high maintenance, many families use artificial Christmas trees. While artificial trees seem like an easy and sustainable alternative, the materials they are made out of can pose health risks. Like many consumer products, artificial trees are often
Asbestos is a group of fibrous minerals that can be found in the environment. The fibers of these minerals are strong, flexible, and heat-resistant, making them useful when spun or woven into sheets. Asbestos was used in building materials, heat-resistant products, and machinery components. When these products break down, asbestos
Asphalt is made of a compacted “aggregate” mixed with a “binder.” The aggregate takes the wear-and-tear of traffic while providing a nonskid surface. It comes from rock quarries, natural gravel, and/or soil. The binder is a type of cement that holds the aggregate together in place and provides waterproofing. It
Atrazine is one of the most common herbicides used in the United States, with over 70 million pounds applied to crops each year. Used mostly in large scale agriculture of crops such as corn, sugarcane, and pineapples, atrazine is the most widely detected herbicide in drinking water. Figures vary, but
Barium is a silver-colored metal which is found in the earth in compounds with other elements. Many barium compounds have industrial uses: barium sulfate is used as a drilling lubricant by the oil and gas industries to facilitate drilling through rock; barium carbonate is a rat poison; and barium oxide
Benzene is a colorless chemical with a sweet odor that is flammable and presents itself in liquid form at normal temperatures and pressures. It is part of a family of chemicals commonly referred to as volatile organic compounds (VOCs), mainly because they evaporate quickly when exposed to air. Although benzene
Pyrethrins are a class of naturally occurring compounds derived from chrysanthemum flowers. They have been used for thousands of years as insecticides and insect repellents. There are also human-made chemicals similar in chemical structure to pyrethrins – called pyrethroids – that are used as more potent insecticides. Today, pyrethrins and
Benzo(a)pyrene (BaP) is a compound in a group of chemicals called polycyclic aromatic hydrocarbons (PAHs). PAHs like BaP are formed in the incomplete burning of coal, oil, gas, or other organic matter. Once formed, they can enter the air, water and soil. The most common way people are exposed to
BPA stands for Bisphenol A and is a man-made chemical produced in large quantities for use primarily in the production of polycarbonate plastics. It is found in a large number of everyday products such as eyewear, water bottles, and epoxy resins that coat some metal food cans, bottle tops, and
Cadmium is a heavy metal found naturally in the earth’s crust. It is usually found as a mineral combined with other elements such as oxygen, chlorine, or sulfur. Cadmium is used in many industries and is essential in the production of batteries, certain alloys, coatings, solar cells, plastic stabilizers, and
Carbon disulfide is a colorless liquid chemical that readily evaporates at room temperature. It occurs naturally during composting and volcanic eruptions, but most carbon disulfide is manufactured by humans for industrial purposes. Most manufactured carbon disulfide is used in the production of rayon, a semi-synthetic fiber used to make clothing.
Carbon monoxide is a toxic gas that is difficult to detect because it has no smell, taste, or color. It can be produced from both natural and human-made sources when carbon fuel – such as gasoline, wood, coal, charcoal, propane, natural gas, or trash – is incompletely burned.
Chromium is a metal element found in rock. A common form is called hexavalent chromium, used in manufacturing settings for textile dyeing, wood preservation, and metal plating. Through release and disposal of waste from these facilities, hexavalent chromium can end up in the surrounding water and soil. People can then
The dose makes the poison is the most basic principle of toxicology. The first chapter in every toxicology textbook discusses how the response to a poison depends on how much of the poison you are exposed to (often referred to as the “dose”). This principle assumes that chemicals act by
Copper is a chemical element and a metal. It is naturally occurring and is found in rocks, soil, water, and air all over the planet. Because it is soft, malleable, and a
good conductor of heat and electricity, it is useful for many purposes. Copper is thought to be the
Creosote is a large mixture of chemicals that is used as a wood preservative in the United States, as well as for roofing, aluminum smelting, and road paving. Houston’s Fifth Ward has been pinpointed as a Cancer Cluster: an area that has a “greater than expected number of cancer cases,” largely
Evaluating the cumulative impacts of exposure to multiple chemicals is perhaps the most difficult task facing toxicologists. The standard approach is to evaluate these risks by conducting a risk assessment or risk evaluation which relies heavily on data from exposure to a single chemical. But this only provides a limited
Cyanide is a chemical usually found in compounds with other chemicals. Cyanide compounds can be found in some bacteria, fungi, algae, and the seeds of stone fruits. One of the most dangerous cyanide compounds is hydrogen cyanide, a colorless gas that smells like almonds.
In a recent issue, we discussed the many challenges in evaluating the adverse health effects that result from exposure to a mixture of toxic chemicals. Despite this, scientists still estimate and assess risks by attempting to compensate for these uncertainties. This is done by assigning an uncertainty factor (UF) to
Di(2-ethylhexyl)phthalate (DEHP) is a manmade chemical and is the most common member of a class of chemicals called phthalates. DEHP is used as a plasticizer, meaning it is added to plastics to make them more flexible, transparent, and durable. DEHP is commonly used as a plasticizer in consumer products such
Diethylene glycol (DEG) is a clear liquid with a sweet taste. It is an effective solvent for resins and adhesives, making them function better. For this reason, DEG is used in many industrial and consumer product settings. It is used in the manufacturing of polymers like polyester and polyurethane to
Dioxins are a group of toxic compounds that share similar and distinct chemical structures. They are mainly byproducts of industrial processes, such as waste incineration. In 1979, the EPA banned products containing Polychlorinated Bihphenyls (PCBs), which is a chemical included under the term dioxin. However, dioxins were a major issue
Dioxins are a group of chemically related compounds formed as a byproduct of industrial processes such as water treatment, paper manufacturing, and waste incineration. If dioxins are not properly captured and stored, they can be released into the environment. Once released into the air, dioxins can travel thousands of miles.
Federal environmental standards were created to protect the environment and human health. Regulations to limit chemicals in water, air, soil, and food set requirements that must be upheld by all levels of government (local, state, tribal, etc.), ideally creating uniform policy and protections for communities across the country. Examples include
Endometrial cancer is an increasingly common form of cancer in developed countries. There are both genetic and environmental risk factors associated with the development of endometrial cancer, and changing the environmental risk factors may be the easiest way of reducing the incidence of endometrial cancer. Pesticides – mixtures of chemicals
The way scientists think about how chemicals cause their toxic effects is changing. Recent scientific research tells us that the traditional notion of how chemicals act is being replaced by a better understanding of the actual features of exposures that influence how chemicals express their adverse effects in people. These
Ethylbenzene is a colorless flammable liquid that comes from coal tar and petroleum. It is primarily used to synthesize chemicals that are used in plastics. Ethylbenzene can also be used in fuels and injection fluid, which is used to release natural gas from the ground. It has industrial uses in
Ethylene Oxide (EtO) is a colorless gas with a slightly sweet odor. It is used in making a variety of products including antifreeze, plastics, detergents, and adhesives. It is also used as a sterilizer for medical equipment and others that cannot be sterilized by steam. Ethylene Oxide can be found
Considering cumulative exposures to low levels mixtures of chemicals is an enormous challenge when evaluating the toxicity of chemicals. Neither the EPA nor ATSDR have guidance on how to evaluate exposure to multiple chemicals simultaneously, or cumulatively over time. The EPA does have its Risk-based Screening Levels (RSLs) that provide
Massive flooding in the state of Kentucky in late July 2022 claimed the lives of 38 people – yet another example of extreme weather events driven by the indiscriminate burning of fossil fuels. We touched upon this broad issue in a previous Toxic Tuesday about the wildfires that scorched the
Formaldehyde is a dangerous chemical that affects the respiratory system, lungs, eyes, and skin. It is classified as a carcinogen, hazardous substance, and hazardous waste. According to the American Cancer Society, Formaldehyde is a colorless, strong smelling gas used in making building materials and many common household products. It is
The last several issues of this series in Toxic Tuesday have addressed the difficulty in interpreting health risks when people are exposed to toxic chemicals. The last issue focused on the failure of the risk assessment approach to address these difficulties and the many critical limitations which make it inadequate
Glyphosate is a chemical found in weed killer products such as RoundUpTM used on farms and home lawns. It gets absorbed by plant leaves, stopping plant growth within hours. Because of its effectiveness, glyphosate is found in widely used products that are easily obtainable. It is used all over the
Glyphosate is a chemical found in weed killer products like RoundUp used on farms and home lawns. 81% of American adults and children have detectable concentrations of glyphosate in their urine. While much is still unknown about the potential health risks of glyphosate exposure, two recently published studies illuminate how
We previously addressed individual variability and how it affects a person’s response to toxic chemicals. Another important factor in toxicology is a person’s individual sensitivity to chemicals. How sensitive a person is to chemical exposure helps determine how susceptible or vulnerable they are to toxic chemicals. Several factors determine how
It’s clear that not everyone responds to the same chemical exposures in the same way. There are many examples of this. The most striking is the person who smoked cigarettes for 30 years and never had breathing problems or developed lung cancer. A major factor in why this happens
It is important to consider multiple chemical exposures when assessing the toxicity of exposure to toxic chemicals. It is also necessary to consider the duration of exposure. How long was a person exposed? What was the concentration of the substance(s) during this period of time are critical to truly understanding