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Toxic Tuesdays

Glycophosate

Toxic Tuesdays

CHEJ highlights several toxic chemicals and the communities fighting to keep their citizens safe from harm.

Glyphosate

Glyphosate is a chemical found in weed killer products such as RoundUpTM used on farms and home lawns. It gets absorbed by plant leaves, stopping plant growth within hours. Because of its effectiveness, glyphosate is found in widely used products that are easily obtainable. It is used all over the United States, but its highest concentrations are in the Midwest and Plains states. When glyphosate-containing weed killers are sprayed to kill plants, it can be inhaled and get on the skin. This can cause skin irritation and respiratory effects. People frequently working with glyphosate may be more likely to develop these respiratory effects. In scientific studies on animals, exposure to glyphosate during pregnancy caused developmental defects in the resulting offspring. Furthermore, there is concern that when combined with other chemicals found in weed killer products, glyphosate may have increased toxicity on humans.

Whether or not exposure to glyphosate increases the risk of cancer is inconclusive. The US EPA classifies it as not likely to cause cancer; however, the International Agency for Research on Cancer (IARC) concluded that it probably does. There have been allegations that large agrochemical corporations that use glyphosate in their products have close relationships with the governmental organizations that conduct the studies regarding glyphosate’s health risks. While more studies and risk assessments may need to be done to be certain of the risks, it is crucial that these studies are done transparently and without bias to protect and inform the public.

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Toxic Tuesdays

Polybrominated diphenyl ethers (PCBEs)

Toxic Tuesdays

CHEJ highlights several toxic chemicals and the communities fighting to keep their citizens safe from harm.

Polybrominated Diphenyl Ethers (PBDE)

Polybrominated Diphenyl Ethers (PBDE) are chemicals that are flame retardants – meaning they are added to different materials to make them less susceptible to fires. PBDEs are found in various everyday materials, such as furniture padding, computers, rugs, and electrical wires. They are a synthetic (not naturally found in the environment) subset of the organobromine compounds, chemicals where a carbon molecule is bonded to a bromine molecule. There are 209 different forms of PBDEs, which vary based on what the carbon-bromine structure looks like.

PBDEs were discovered in the 1970s, and since then, several of them have been phased out of production (PentaBDE and OctaBDE), but other versions (such as DecaBDE) are still being manufactured. While some states, such as California and Washington, have banned specific forms of PBDEs from production, there is no national restriction on the production of this chemical as of 2023. It’s also important to note that even for PBDEs that have been banned or phased out of production, the waste from production and manufacturing remains in the environment and causes harm.

The lack of national attention to this class of chemicals is concerning because of the mounting evidence that PBDEs have negative impacts on human health. For example, these chemicals are thought to be endocrine-disrupting. The endocrine system, which oversees the regulation of hormones, is vital to human health. When this system is damaged, it can cause various adverse health effects, such as cancer, reproductive damage, and neurological damage. A case-control study found that exposure to PBDEs was associated with an increased risk of breast cancer among post-menopausal women. Another study found that the BDE-28 compound was associated with an increased risk of papillary thyroid cancer. As for reproductive health, a study on infants reported that pregnancies that had PBDE chemicals in the umbilical cords, those infants were more likely to have lower birth weights. And a chemical that causes fetal abnormalities is called a teratogen, although PBDE does not carry this classification by the Environmental Protection Agency. Evidence of neurological damage has also been in animal studies, where PBDE was found to cause neurotoxic effects on memory, attention, and leaning ability.

Exposure to PBDEs during pregnancy is only one route of exposure to this chemical. Because PBDEs decompose slowly in the environment, they bioaccumulate and build up in the food chain. Fish and other marine life are especially prone to bioaccumulation. Thus, PBDE contamination could be of concern for people who consume a lot of seafood or rely on it as their primary protein source. Another way that people can be exposed to the chemicals is through water. PBDE waste can seep through the ground and contaminate the groundwater sources. Another exposure route, which accounts for an estimated 80% to 90% of exposure for the population, is inhaling contaminated dust particles. For example, PBDE can be found in the dust that accumulates in homes. One study found that individuals who had higher levels of PBDE in the dust at their houses had higher levels of the chemical in their blood serum levels.

PBDEs are considered persistent organic pollutants (POP), and many communities are fighting against this contamination in their backyards. For example, the Alaska Community Action on Toxins (ACAT) has been advocating for years to ban the use of PBDEs in the state. Another group that has been advocating for the ban on PBDEs are first responders, specifically fire-fighter organizations. When blood samples were taken from firefighters, they had brominated dioxins and furans in their bloodstreams. Fire fighters are more exposed to these chemicals because when a house fire occurs, all of the products that have PBDEs in them, such as furniture upholstery, burn up and release these toxic chemicals into the air that the first responders breathe in.

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